Quality control techniques for filling micro titre plates

The filling procedure of micro titre plates in applications of medical diagnostics or biotechnology requires the precise control of the transferred µl-volumes. As recently shown, the method of heat transfer thermography, that displays the different thermal properties of titre plate and liquid, can satisfy the corresponding demands on measurement precision. Currently an automated experimental rig that contains a multi-channel dispen­sing-system and integrated imaging acquisition and processing has been built and tested. Key activities are the optimization of the test rig, development of processing algorithms and experimental testing.